The device is a proprietary design by Kurt Garrett.
It is made of stainless steel erected on an adjustable
sliding vertical spine. All rights reserved.
Wednesday, March 30, 2011
Wednesday, January 5, 2011
NOAA Publication: HPUV Proposed Studies by Kurt Garrett
HIGH PERFORMANCE UV (HPUV) INACTIVATION OF E. COLI. Kurt A. Garrett, Cheryl M. Davis and De Lois M. Powell, Department of Natural and Physical Sciences, Shaw University, Raleigh, NC
The use of ultraviolet light for inactivation of microorganisms is well documented in the literature. Ultraviolet light used for inactivation is sometimes called germicidal UV or UV254 (the specific wavelength known to have the most lethal effect on bacteria, fungi and viruses).
While this band of invisible light is part of the sun’s spectral energy, artificial sources of germicidal UV come from manufacturers such as Sylvania and General Electric. The greatest users of germicidal UV lamps are wastewater treatment facilities seeking alternative methods of disinfection that reduce the need for chlorine and chlorine derivatives. The disinfection mechanism generally points to the disruption of the microorganism’s DNA. In turn, the disruption of microbial DNA prevents replication and can cause ‘death’. Early UV light inactivation research was set back when conventional ultraviolet lamps performed below expectation. This failure was traced to lamp design. While researchers sought intense high-energy germicidal UV light, manufacturers designed low-energy UV lamps, primarily used for wastewater disinfection. In research typical inactivation times, using conventional germicidal UV lamps, range from 20 minutes to several days for virus and similar times for bacteria.
Recently, we tested a new lamp system, High Performance Ultraviolet Light (HPUV; CSMO, Inc.) and found it to reduce 106 colonies of herpes simplex virus (HSV) in three seconds. We are proposing use of the HPUV for inactivation of E. coli. Our studies will measure inactivation initiation, inactivation optimum and hyper-inactivation. HPUV is expected to result in quicker inactivation times for E. coli than conventional UV lamps. This data will allow us to construct a response curve for E. coli when using HPUV inactivation. Future research will use these data to determine inactivation conditions that preserve important protein triggers of the cellular immune response.
Monday, January 3, 2011
HPUV™ (high performance ultravioletlight) by Kurt A. Garrett
Microorganisms encompass a wide variety of unique structures and can be grouped into five basic groups: bacteria, virus, fungi, protozoa, and algae. A microorganism is composed of the cell-wall, cytoplasmic membrane and the cell's genetic material, nucleic acid. It is this genetic material or DNA that is affected by the Ultraviolet light. As UV-C penetrates through the cell wall, it causes molecular rearrangement of the microorganism's DNA thus preventing reproduction. If a cell can not reproduce, it is considered to be microbiologically dead. Due to individual cell makeup, different levels of UV energy are required for destruction. The effectiveness of UV microbial destruction is a product of both time and intensity. The intensity of UV-C light is measured in micro-watts per square centimeter and the time is measured in seconds. Hence the amount of ultraviolet light necessary to kill a particular microorganism is reported in units of micro-watt seconds per square centimeter; this is known as the dose. The following table shows the dose required to kill common microorganisms.
HPUV™ : Effective Against Nosocomial Infections by Kurt A. Garrett
The article listed below is an example of unusual circumstances. But then similar and worse circumstances are not uncommon. Extrapolate the idea and we all can remember helpless feelings from the anthrax sporing. My small company is not standing by idle. We are having success at rapidly and effectively inactivating nosocomial aquired infections at greater than 2-3 log reductions in seconds! We are seeking collaboration with private investigators who want to commercialize new medical products and services. Contact: kurtgarrett@hpuvinc.com or fax:(919)546.8258.
FAYETTEVILLE, N.C. — A tough strain of skin infection that's called the “Super Bug” has become the most common form of skin infection among adult patients in hospitals nationwide, health officials say, but it can prey on people big and small.
One blister showed up on Emma Berrier’s forehead, then another on her chin. Celia Berrier took her 6-month-old daughter to the doctor.
"He didn't even need to do a culture. He just knew it was MRSA," Celia said Wednesday.
It’s pronounced MER-sah and stands for “methicillin-resistant Staphylococcus aureus,” a tough strain of staph infection unfazed by many antibiotics.
Emma’s mom believes Emma caught MRSA from another child whose MRSA has worsened.
"It progressed and has moved to other parts of his body, and he's just very ill,” Berrier said.
MRSA usually infects the skin and causes large pimples or boils. It can, however, enter through wounds, spread through the bloodstream and even infect the lungs.
"The [bacteria] is everywhere. It's on the skin, in the nose" normally, said Dr. Lan Tran-Phu of the Cumberland County Health Department.
FAYETTEVILLE, N.C. — A tough strain of skin infection that's called the “Super Bug” has become the most common form of skin infection among adult patients in hospitals nationwide, health officials say, but it can prey on people big and small.
One blister showed up on Emma Berrier’s forehead, then another on her chin. Celia Berrier took her 6-month-old daughter to the doctor.
"He didn't even need to do a culture. He just knew it was MRSA," Celia said Wednesday.
It’s pronounced MER-sah and stands for “methicillin-resistant Staphylococcus aureus,” a tough strain of staph infection unfazed by many antibiotics.
Emma’s mom believes Emma caught MRSA from another child whose MRSA has worsened.
"It progressed and has moved to other parts of his body, and he's just very ill,” Berrier said.
MRSA usually infects the skin and causes large pimples or boils. It can, however, enter through wounds, spread through the bloodstream and even infect the lungs.
"The [bacteria] is everywhere. It's on the skin, in the nose" normally, said Dr. Lan Tran-Phu of the Cumberland County Health Department.
HPUV™ Challenges Conventional Medical & Science Wisdom by Kurt A. Garrett November 2010
I knew I was facing a steep incline in getting some people to see my vision when a former Director of the NC Biotechnology Center told me that what I was doing "...is not biotechnology" and a Cancer Center Director told me that I had "...things figured wrong". I rebounded a year later and found the inquisitiveness and gentle nature of Dr. Steve Bachenheimer, a microbiologist, who entertained my request to test HPUV™. The results were a landmark, HPUV™ inactivated one million colonies of herpes simplex virus, HSV, in 3 seconds! Since that day the device has not met a microbial target it could not rapidly inactivate. But the highly efficient inactivation was only a proof of concept for a much larger vision for HPUV™. Biotechnology and medical treatment offered immense landscapes for development of novel devices, treatment, diagnostics and new insight. The gap of medical and scientific information to be garnered from HPUV™ is still available.
Conventional thinking has been slow to accept HPUV™'s promise. Instead, those contacted have been unwilling to collaborate or continue proof of concepts. While the cost of development is minimal, ask Bachenheimer, and the proposals are simple, nebulous excuses or 'sudden loss of interest' following confidential disclosures dash hopes of going forward. Until there is a willingness to evaluate unconventional technologies like HPUV™ the poor state of managing infection costs in the billions annually, illness and loss of life described below will persist.
Dr. Bachenheimer has retired and what a shame because open minds are hard to find.
Nosocomial Infection Statistics4.5 hospital acquired infections per 100 admitted people
1.7 million people infected per year
99,000 people die each year (6%)
Estimated as low as $5.7 to as high as $45 billion in medical cost per year
Coronary artery disease ~ $17.5 billion
Congestive heart failure ~ $11.2 billion
Stroke ~ $6.7 billion
Diabetes mellitus with complications ~ 4.2 billion
Pseudomona aeruginosa
136,000 people infected via HAIs (~8000 deaths)
Also infects immunocompromised patients
-Chemotherapy
-Cystic fibrosis
-AIDS
Plants (lettuce, beans, etc)
Animals (mice, insects, worm, etc.)
Conventional thinking has been slow to accept HPUV™'s promise. Instead, those contacted have been unwilling to collaborate or continue proof of concepts. While the cost of development is minimal, ask Bachenheimer, and the proposals are simple, nebulous excuses or 'sudden loss of interest' following confidential disclosures dash hopes of going forward. Until there is a willingness to evaluate unconventional technologies like HPUV™ the poor state of managing infection costs in the billions annually, illness and loss of life described below will persist.
Dr. Bachenheimer has retired and what a shame because open minds are hard to find.
Nosocomial Infection Statistics4.5 hospital acquired infections per 100 admitted people
1.7 million people infected per year
99,000 people die each year (6%)
Estimated as low as $5.7 to as high as $45 billion in medical cost per year
Coronary artery disease ~ $17.5 billion
Congestive heart failure ~ $11.2 billion
Stroke ~ $6.7 billion
Diabetes mellitus with complications ~ 4.2 billion
Pseudomona aeruginosa
136,000 people infected via HAIs (~8000 deaths)
Also infects immunocompromised patients
-Chemotherapy
-Cystic fibrosis
-AIDS
Plants (lettuce, beans, etc)
Animals (mice, insects, worm, etc.)
LUNAR ECLIPSE REVISITED by Kurt Garrett 12/21/2010
All the essentials needed for a night/morning observing the 2010 lunar eclipse in the northern hemisphere.
A picture is worth a thousand words:
A picture is worth a thousand words:
HPUV™ Rapid Inactivation of Herpes Simplex Virus (HSV) by Kurt Garrett
Herpes simplex Test at UNC-CH
The HSV test validated the high efficacy of HPUV™ and according to Dr. Bachenheimer, gave the fastest performance in his experience, one million colonies inactivated in 3 seconds.
TABLE 1. Virus HSV Inactivation Table
5.48 X 103 pfu/well 5.48 X 102 pfu/well 5.48 X 101 pfu/well
0.1 33
0.2 32
3.0 35
30.0 0
60.0 0
90.0 0
120.0 0
300.0 0
730.0 0
We can realize opportunities for HPUV™ to increase the breath of scientific knowledge by commercializing a number of related products. Researchers will find usefulness in our product/instruments that will give them the capacity to routinely and easily disrupt DNA. They will marvel at the possibility of manipulating various types of biological materials especially in their efforts to engineer machines for a myriad of medical and scientific endeavors.
TABLE 1. Virus HSV Inactivation Table
5.48 X 103 pfu/well 5.48 X 102 pfu/well 5.48 X 101 pfu/well
0.1 33
0.2 32
3.0 35
30.0 0
60.0 0
90.0 0
120.0 0
300.0 0
730.0 0
We can realize opportunities for HPUV™ to increase the breath of scientific knowledge by commercializing a number of related products. Researchers will find usefulness in our product/instruments that will give them the capacity to routinely and easily disrupt DNA. They will marvel at the possibility of manipulating various types of biological materials especially in their efforts to engineer machines for a myriad of medical and scientific endeavors.
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